Journal of Pediatric Nursing
Volume 27, Issue 1 , Pages 3-17, February 2012

The Effectiveness of Glucose in Reducing Needle-Related Procedural Pain in Infants

  • Manal Ibrahim Kassab, RN, BSN, MSN, PhD

      Affiliations

    • Faculty of Nursing, Midwifery and Health, University of Technology, Sydney, Sydney NSW, Australia
    • Corresponding Author InformationCorresponding author. Manal Ibrahim Kassab, RN, BSN, MSN, PhD.
    • ,
  • Jessica K. Roydhouse, BA, MPH (Hons)

      Affiliations

    • Cancer Nursing Research Unit, Sydney Nursing School, University of Sydney, Sydney NSW, Australia
    • Sydney Cancer Centre, Royal Prince Alfred Hospital, Camperdown NSW, Australia
    • ,
  • Cathrine Fowler, BEd, MEd, PhD

      Affiliations

    • Faculty of Nursing, Midwifery and Health, University of Technology, Sydney, Sydney NSW, Australia
    • Tresillian Family Care Centres, Belmore NSW, Australia
    • ,
  • Maralyn Foureur, BA, Grad Dip Clin Epi, PhD

      Affiliations

    • Centre for Midwifery, Child and Family Health, Faculty of Nursing, Midwifery and Health, University of Technology, Sydney, Sydney NSW, Australia

published online 04 February 2011.

This systematic review examined the effectiveness of glucose in relieving needle-associated pain in infants. Meta-analysis was not undertaken, and there was variation in dose, administration method, concentration, and outcome measurement. Glucose was more effective than placebo in relieving infant pain as measured by behavioral outcomes, but there were mixed findings for physiological outcomes. Based on these findings, 25%–50% glucose appears effective for infant pain management.

Key words: Analgesia, Infant, Glucose, Systematic review

 

PII: S0882-5963(10)00324-6

doi:10.1016/j.pedn.2010.10.008

Journal of Pediatric Nursing
Volume 27, Issue 1 , Pages 3-17, February 2012

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